POLR2DP1

Across TCGA patient cohorts, POLR2DP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,015 significant associations in total. STAD shows the largest number of these associations.

The most reproducible POLR2DP1-associated GO terms across cancer lineages are Regulation of DNA repair, Regulation of double-strand break repair, and Protein polymerization. Each is linked with POLR2DP1 in more than 10 cancer types. Because this analysis shows association rather than direction, both POLR2DP1-to-partner and partner-to-POLR2DP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by POLR2DP1-low versus POLR2DP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR2DP1→partner) and Y-score (partner→POLR2DP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of DNA repair →	+0.055	+0.107	<.001	<.001	3	11
STAD	Regulation of double-strand break repair →	+0.053	+0.114	<.001	<.001	3	10
STAD	Protein polymerization →	+0.052	+0.093	<.001	<.001	3	10
STAD	Neural precursor cell proliferation →	+0.038	+0.112	<.001	<.001	3	10
STAD	Regulation of protein serine/threonine kinase activity →	+0.047	+0.116	<.001	<.001	3	10
STAD	Regulation of protein ubiquitination →	+0.060	+0.111	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,015 associations by consensus.

Regulation of DNA repair by POLR2DP1 expression — STAD

Explore this box plot interactively →