POLR2D

Across TCGA patient cohorts, POLR2D RNA expression is significantly associated with the protein abundance of many other proteins, with 18,511 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POLR2D-associated proteins across cancer lineages are RIF1, ATAD2, and ILKAP. Each is linked with POLR2D in more than 7 cancer types. Because this analysis shows association rather than direction, both POLR2D-to-partner and partner-to-POLR2D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR2D versus RIF1 in LSCC, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR2D→partner) and Y-score (partner→POLR2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RIF1 →	+0.512	+0.626	<.001	<.001	3	8
GBM	ATAD2 →	+0.414	+0.271	<.001	<.001	3	8
UCEC	ILKAP →	+0.387	+0.404	<.001	<.001	3	8
GBM	MCM3 →	+0.801	+0.440	<.001	<.001	3	8
BRCA	UBE2T →	+0.841	+0.381	<.001	.001	3	7
LSCC	GMPS →	+0.474	+0.615	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,511 associations by consensus.

POLR2D vs RIF1 — LSCC

Explore this scatter interactively →