POLR1C

Across TCGA patient cohorts, POLR1C RNA expression is significantly associated with the RNA expression of many other genes, with 19,533 significant associations in total. ACC shows the largest number of these associations.

The most reproducible POLR1C-associated genes across cancer lineages are BYSL, HSP90AB1, and MRTO4. Each is linked with POLR1C in more than 33 cancer types. Because this analysis shows association rather than direction, both POLR1C-to-partner and partner-to-POLR1C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR1C versus BYSL in ACC, with a Pearson correlation of 0.91.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR1C→partner) and Y-score (partner→POLR1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	BYSL →	+1.471	+1.095	<.001	<.001	3	34
LIHC	HSP90AB1 →	+0.907	+0.686	<.001	<.001	3	34
ACC	MRTO4 →	+1.051	+1.009	<.001	<.001	3	33
ACC	MRPL2 →	+0.967	+1.093	<.001	<.001	3	33
ACC	XPO5 →	+1.261	+0.995	<.001	<.001	3	33
ACC	MRPL14 →	+1.458	+1.072	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,533 associations by consensus.

POLR1C vs BYSL — ACC

Explore this scatter interactively →