POLR1C

Across TCGA patient cohorts, POLR1C RNA expression is significantly associated with the protein abundance of many other proteins, with 19,387 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POLR1C-associated proteins across cancer lineages are ZNF318_S709, XPO5, and NELFB. Each is linked with POLR1C in more than 9 cancer types. Because this analysis shows association rather than direction, both POLR1C-to-partner and partner-to-POLR1C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR1C versus ZNF318_S709 in OV, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR1C→partner) and Y-score (partner→POLR1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZNF318_S709 →	+0.691	+0.427	<.001	.001	3	10
LSCC	XPO5 →	+0.765	+0.849	<.001	<.001	3	10
GBM	NELFB →	+0.331	+0.282	<.001	<.001	3	9
LSCC	ZNF318 →	+0.482	+0.842	<.001	<.001	3	8
HNSC	ZNF638 →	+0.318	+0.699	<.001	<.001	3	8
GBM	RNF20 →	+0.255	+0.356	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,387 associations by consensus.

POLR1C vs ZNF318_S709 — OV

Explore this scatter interactively →