POLM

Across TCGA patient cohorts, POLM RNA expression is significantly associated with the protein abundance of many other proteins, with 8,953 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible POLM-associated proteins across cancer lineages are NUDCD3, VEZF1, and GTF2I. Each is linked with POLM in more than 5 cancer types. Because this analysis shows association rather than direction, both POLM-to-partner and partner-to-POLM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLM versus NUDCD3 in UCEC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLM→partner) and Y-score (partner→POLM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NUDCD3 →	+0.238	+0.415	.001	.002	2	6
GBM	VEZF1 →	+0.379	+0.278	.007	.006	3	5
GBM	GTF2I →	+0.408	+0.368	<.001	.001	3	4
LSCC	ZNF316_S112 →	+0.339	+0.415	.001	.001	3	4
LUAD	RPL26 →	-0.816	-0.588	<.001	<.001	3	3
BRCA	SBSPON →	+0.644	+0.443	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,953 associations by consensus.

POLM vs NUDCD3 — UCEC

Explore this scatter interactively →