POLK

Across TCGA patient cohorts, POLK RNA expression is significantly associated with the protein abundance of many other proteins, with 14,416 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible POLK-associated proteins across cancer lineages are CERT1, TBCA, and RPL7. Each is linked with POLK in more than 6 cancer types. Because this analysis shows association rather than direction, both POLK-to-partner and partner-to-POLK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLK versus CERT1 in UCEC, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLK→partner) and Y-score (partner→POLK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CERT1 →	+0.469	+0.503	<.001	<.001	3	7
PDAC	TBCA →	+0.239	+0.318	.001	.002	3	5
GBM	RPL7 →	-0.376	-0.274	<.001	<.001	3	5
BRCA	AIDA →	+0.290	+0.634	<.001	<.001	3	5
LUAD	LRPPRC →	-0.439	-0.358	<.001	<.001	3	5
LSCC	NRP1 →	+0.301	+0.357	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,416 associations by consensus.

POLK vs CERT1 — UCEC

Explore this scatter interactively →