POLH

Across TCGA patient cohorts, POLH RNA expression is significantly associated with the protein abundance of many other proteins, with 12,780 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POLH-associated proteins across cancer lineages are ANP32E, TBCC, and UBE2T. Each is linked with POLH in more than 6 cancer types. Because this analysis shows association rather than direction, both POLH-to-partner and partner-to-POLH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLH versus ANP32E in BRCA, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLH→partner) and Y-score (partner→POLH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ANP32E →	+0.584	+0.501	.008	.004	1	7
LSCC	TBCC →	+0.302	+0.538	<.001	<.001	3	5
GBM	UBE2T →	+0.758	+0.462	.001	<.001	3	5
LSCC	XPO5 →	+0.556	+0.483	<.001	<.001	3	5
LSCC	ZNF318 →	+0.286	+0.433	<.001	<.001	3	5
LSCC	CDC73 →	+0.352	+0.452	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,780 associations by consensus.

POLH vs ANP32E — BRCA

Explore this scatter interactively →