POLD2

Across TCGA patient cohorts, POLD2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,411 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POLD2-associated genes across cancer lineages are CENPM, DTL, and POLD3. Each is linked with POLD2 in more than 9 cancer types. Because this analysis shows association rather than direction, both POLD2-to-partner and partner-to-POLD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLD2 versus CENPM in UCEC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POLD2→partner) and Y-score (partner→POLD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPM →	+1.059	+0.230	<.001	<.001	3	10
BRCA	DTL →	+0.998	+0.263	<.001	<.001	3	10
OV	POLD3 →	+0.858	+0.488	<.001	.003	3	10
UCEC	CDKN3 →	+0.960	+0.248	<.001	<.001	3	9
BRCA	GINS1 →	+0.920	+0.382	<.001	<.001	3	9
UCEC	ASF1B →	+1.112	+0.285	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,411 associations by consensus.

POLD2 vs CENPM — UCEC

Explore this scatter interactively →