POGZ

Across TCGA cell cohorts, POGZ RNA expression is significantly associated with the go_rna of many other GO terms, with 5,529 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible POGZ-associated GO terms across cancer lineages are Heterochromatin organization, Epigenetic regulation of gene expression, and Positive regulation of double-strand break repair. Each is linked with POGZ in more than 18 cancer types. Because this analysis shows association rather than direction, both POGZ-to-partner and partner-to-POGZ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin organization grouped by POGZ-low versus POGZ-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POGZ→partner) and Y-score (partner→POGZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Heterochromatin organization →	+0.067	+0.862	<.001	<.001	3	19
BONE	Epigenetic regulation of gene expression →	+0.082	+1.073	<.001	<.001	3	19
LUNG_NSCLC_LUSC	Positive regulation of double-strand break repair →	+0.081	+1.364	.001	.002	3	18
BONE	Heterochromatin formation →	+0.072	+1.249	.009	<.001	3	18
BONE	Negative regulation of gene expression, epigenetic →	+0.083	+0.996	<.001	.004	3	18
BONE	Pre-mRNA catabolic process →	+0.214	+1.231	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,529 associations by consensus.

Heterochromatin organization by POGZ expression — OVARY

Explore this box plot interactively →