POGLUT3

Across TCGA pan-cancer cohorts, POGLUT3 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated POGLUT3 data layer compared with 22 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher POGLUT3 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated POGLUT3 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

UCEC, GBM, and CCRCC are the cancer types where POGLUT3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	III,IV	0.247	1.000	.008	20	view →
GBM	DFS	Quartile	All	0.648	0.864	.007	4	view →
CCRCC	DFS	Median	IV	0.781	0.220	.017	3	view →
LSCC	OS	Tertile	All	0.684	1.000	.042	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

POGLUT3–UCEC (DFS)

Open the UCEC breakdown →