POGLUT3

Across TCGA patient cohorts, POGLUT3 mutation is significantly associated with the RNA expression of many other genes, with 1,268 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POGLUT3-associated genes across cancer lineages are MIR4282, RN7SL265P, and RNU6-1085P. Each is linked with POGLUT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both POGLUT3-to-partner and partner-to-POGLUT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4282 grouped by POGLUT3-low versus POGLUT3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POGLUT3→partner) and Y-score (partner→POGLUT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR4282 →	+0.395	+5.993	<.001	.001	3	2
UCEC	RN7SL265P →	+0.270	+2.377	.008	.001	3	2
BLCA	RNU6-1085P →	+0.601	+4.973	<.001	.009	3	2
SKCM	RNU1-20P →	+0.251	+4.513	.002	.009	3	2
UCEC	LIN7C →	+0.623	+3.815	.003	<.001	3	1
UCEC	PGAP2 →	+0.536	+2.818	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,268 associations by consensus.

MIR4282 by POGLUT3 expression — SKCM

Explore this box plot interactively →