POGLUT3

Across TCGA cell cohorts, POGLUT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,716 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible POGLUT3-associated GO terms across cancer lineages are Negative regulation of telomere capping, Negative regulation of mitotic nuclear division, and Regulation of chromosome segregation. Each is linked with POGLUT3 in more than 10 cancer types. Because this analysis shows association rather than direction, both POGLUT3-to-partner and partner-to-POGLUT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of telomere capping grouped by POGLUT3-low versus POGLUT3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POGLUT3→partner) and Y-score (partner→POGLUT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of telomere capping →	+0.087	+1.122	<.001	.001	3	11
LUNG_NSCLC_LUSC	Negative regulation of mitotic nuclear division →	+0.163	+2.478	.002	.001	3	11
BREAST	Regulation of chromosome segregation →	+0.108	+1.504	.002	.001	3	11
BREAST	Mitotic chromosome condensation →	+0.120	+1.411	.001	<.001	3	10
SKIN	Spindle checkpoint signaling →	+0.106	+1.008	.001	.002	3	10
SKIN	Mitotic spindle assembly checkpoint signaling →	+0.136	+1.191	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,716 associations by consensus.

Negative regulation of telomere capping by POGLUT3 expression — SOFT_TISSUE

Explore this box plot interactively →