POGLUT3

Across TCGA cell cohorts, POGLUT3 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible POGLUT3-associated genes across cancer lineages are MROH2B, KRT26, and NT5C1A. Each is linked with POGLUT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both POGLUT3-to-partner and partner-to-POGLUT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MROH2B grouped by POGLUT3-low versus POGLUT3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POGLUT3→partner) and Y-score (partner→POGLUT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	MROH2B →	+0.087	+4.643	<.001	.005	3	1
OVARY	KRT26 →	+0.009	+3.990	<.001	.003	3	1
LARGE_INTESTINE	NT5C1A →	+0.027	+3.684	.009	.006	3	1
LARGE_INTESTINE	CLDN17 →	+0.062	+3.930	<.001	.003	3	1
LARGE_INTESTINE	PYDC1 →	+0.249	+4.347	<.001	.001	3	1
LARGE_INTESTINE	OR1L6 →	+0.022	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

MROH2B by POGLUT3 expression — BLOOD_Lymphoma

Explore this box plot interactively →