POGLUT2

Across TCGA patient cohorts, POGLUT2 mutation is significantly associated with the RNA expression of many other genes, with 1,899 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POGLUT2-associated genes across cancer lineages are CCL5, FRG1HP, and HMGB1P50. Each is linked with POGLUT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both POGLUT2-to-partner and partner-to-POGLUT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL5 grouped by POGLUT2-low versus POGLUT2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POGLUT2→partner) and Y-score (partner→POGLUT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCL5 →	+0.879	+1.673	.003	.003	3	2
UCEC	FRG1HP →	+0.415	+2.243	.002	.005	3	2
LUAD	HMGB1P50 →	+0.090	+3.415	.003	.009	3	2
COAD	MIA-RAB4B →	+0.481	+2.403	<.001	.009	3	2
UCEC	PHF5A →	+0.485	+3.098	<.001	<.001	3	2
UCEC	CEP76 →	+0.339	+1.662	.005	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,899 associations by consensus.

CCL5 by POGLUT2 expression — UCEC

Explore this box plot interactively →