POGLUT2

Across TCGA cell cohorts, POGLUT2 mutation is significantly associated with the RNA expression of many other genes, with 125 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible POGLUT2-associated genes across cancer lineages are CBY1, UHRF1BP1L, and C12orf65. Each is linked with POGLUT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both POGLUT2-to-partner and partner-to-POGLUT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CBY1 grouped by POGLUT2-low versus POGLUT2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POGLUT2→partner) and Y-score (partner→POGLUT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CBY1 →	+0.719	+3.299	<.001	.004	3	1
LARGE_INTESTINE	UHRF1BP1L →	+0.579	+3.212	.004	.006	3	1
LARGE_INTESTINE	C12orf65 →	+0.503	+3.212	.001	.006	3	1
LARGE_INTESTINE	CCDC59 →	+0.527	+3.212	.001	.006	3	1
LARGE_INTESTINE	RWDD2A →	+0.522	+3.299	.002	.004	3	1
LARGE_INTESTINE	PPA2 →	+0.775	+3.234	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 125 associations by consensus.

CBY1 by POGLUT2 expression — LARGE_INTESTINE

Explore this box plot interactively →