POGLUT1

Across TCGA pan-cancer cohorts, POGLUT1 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated POGLUT1 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher POGLUT1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated POGLUT1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PDAC show a favorable association.

LUAD, COAD, and HNSC are the cancer types where POGLUT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	II,III,IV	0.673	0.947	.003	20	view →
COAD	DFS	Median	IV	0.565	1.000	.028	6	view →
HNSC	DFS	Median	All	0.851	0.710	.021	6	view →
PDAC	OS	Tertile	IV	0.905	0.231	.024	6	view →
LSCC	OS	Quartile	III,IV	0.421	0.986	.006	6	view →
GBM	DFS	Tertile	All	0.735	0.896	.024	5	view →
UCEC	OS	Tertile	II,III,IV	0.557	1.000	.034	4	view →
CCRCC	OS	Tertile	All	0.864	0.983	.021	1	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

POGLUT1–LUAD (DFS)

Open the LUAD breakdown →