POGLUT1

Across TCGA patient cohorts, POGLUT1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,774 significant associations in total. GBM shows the largest number of these associations.

The most reproducible POGLUT1-associated genes across cancer lineages are KLF12, TMEM39A, and NEPRO. Each is linked with POGLUT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both POGLUT1-to-partner and partner-to-POGLUT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POGLUT1 versus KLF12 in UCEC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POGLUT1→partner) and Y-score (partner→POGLUT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KLF12 →	+1.162	+0.363	<.001	<.001	3	5
HNSC	TMEM39A →	+0.566	+0.252	<.001	<.001	3	5
LSCC	NEPRO →	+0.525	+0.392	<.001	<.001	3	5
UCEC	GDA →	-1.319	-0.325	<.001	<.001	3	4
HNSC	CCDC92 →	+0.649	+0.247	.001	.003	3	4
LSCC	PDZRN3 →	+0.808	+0.272	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,774 associations by consensus.

POGLUT1 vs KLF12 — UCEC

Explore this scatter interactively →