POGLUT1

Across TCGA cell cohorts, POGLUT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,588 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible POGLUT1-associated GO terms across cancer lineages are Regulation of telomere maintenance, Negative regulation of telomere maintenance, and Microtubule polymerization. Each is linked with POGLUT1 in more than 13 cancer types. Because this analysis shows association rather than direction, both POGLUT1-to-partner and partner-to-POGLUT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere maintenance grouped by POGLUT1-low versus POGLUT1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POGLUT1→partner) and Y-score (partner→POGLUT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of telomere maintenance →	+0.078	+1.371	<.001	<.001	3	14
STOMACH	Negative regulation of telomere maintenance →	+0.069	+0.593	.001	.006	3	13
LARGE_INTESTINE	Microtubule polymerization →	+0.104	+0.705	<.001	<.001	3	13
BLOOD_Leukemia	Protein desumoylation →	+0.076	+0.628	<.001	<.001	2	14
PANCREAS	Protein localization to chromosome →	+0.112	+0.587	<.001	.007	3	13
UPPER_AERODIGESTIVE_TRACT	Establishment of RNA localization →	+0.084	+0.989	.002	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,588 associations by consensus.

Regulation of telomere maintenance by POGLUT1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →