POGLUT1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, POGLUT1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible POGLUT1-associated genes across cancer lineages are OR6P1, TRPC7, and ZNF835. Each is linked with POGLUT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both POGLUT1-to-partner and partner-to-POGLUT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6P1 grouped by POGLUT1-low versus POGLUT1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POGLUT1→partner) and Y-score (partner→POGLUT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaOR6P1 →+0.012+5.201<.001.00631
BLOOD_LeukemiaTRPC7 →+0.036+5.201<.001.00631
STOMACHZNF835 →+0.121+4.442<.001.00231
STOMACHFOLR2 →+0.037+3.632.001.00931
STOMACHGOLGA6L6 →+0.051+3.794.002.00331
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OR6P1 by POGLUT1 expression — BLOOD_Leukemia

Box plot of OR6P1 in POGLUT1-low vs POGLUT1-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration