POGK

Across TCGA patient cohorts, POGK mutation is significantly associated with the RNA expression of many other genes, with 3,988 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POGK-associated genes across cancer lineages are OR2A41P, MIR3165, and OR5A2. Each is linked with POGK in more than 1 cancer types. Because this analysis shows association rather than direction, both POGK-to-partner and partner-to-POGK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2A41P grouped by POGK-low versus POGK-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POGK→partner) and Y-score (partner→POGK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	OR2A41P →	+0.396	+3.450	<.001	.008	3	2
STAD	MIR3165 →	+0.663	+3.692	.009	.007	3	2
BRCA	OR5A2 →	+0.037	+5.365	<.001	.002	3	2
BLCA	HIGD1AP13 →	+0.123	+4.492	<.001	.005	3	2
CESC	MIR6806 →	+0.917	+4.824	<.001	<.001	3	2
COAD	MIR193A →	+1.147	+4.048	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,988 associations by consensus.

OR2A41P by POGK expression — STAD

Explore this box plot interactively →