Across TCGA patient cohorts, POFUT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,707 significant associations in total. GBM shows the largest number of these associations.

The most reproducible POFUT2-associated proteins across cancer lineages are PTK7, CRTAP, and POGLUT3. Each is linked with POFUT2 in more than 4 cancer types. Because this analysis shows association rather than direction, both POFUT2-to-partner and partner-to-POFUT2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POFUT2→partner) and Y-score (partner→POFUT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PTK7 →	+0.388	+0.359	<.001	.001	3	5
BRCA	CRTAP →	+0.594	+0.595	<.001	<.001	3	5
BRCA	POGLUT3 →	+0.393	+0.658	<.001	<.001	3	5
PDAC	CCN1 →	+0.640	+0.392	<.001	<.001	3	4
OV	SERPINF1 →	+0.776	+0.724	.002	.001	3	4
CCRCC	C1R →	+0.510	+0.253	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,707 associations by consensus.

Exploration

POFUT2 survival (RNA) · tumor vs normal (RNA) · all POFUT2 data types