Across TCGA patient cohorts, POFUT2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,213 significant associations in total. GBM shows the largest number of these associations.

The most reproducible POFUT2-associated genes across cancer lineages are TMEM45A, RCN3, and FN1. Each is linked with POFUT2 in more than 7 cancer types. Because this analysis shows association rather than direction, both POFUT2-to-partner and partner-to-POFUT2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POFUT2→partner) and Y-score (partner→POFUT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TMEM45A →	+1.270	+0.273	<.001	<.001	3	8
OV	RCN3 →	+1.075	+0.457	.002	.003	3	7
HNSC	FN1 →	+2.045	+0.390	<.001	<.001	3	6
GBM	LOXL1 →	+1.090	+0.271	<.001	.005	3	6
HNSC	COL5A1 →	+1.562	+0.427	<.001	<.001	3	6
HNSC	COL6A1 →	+1.256	+0.359	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,213 associations by consensus.

Exploration

POFUT2 survival (RNA) · tumor vs normal (RNA) · all POFUT2 data types