POFUT1

Across TCGA patient cohorts, POFUT1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,850 significant associations in total. COAD shows the largest number of these associations.

The most reproducible POFUT1-associated genes across cancer lineages are TM9SF4, ASXL1, and MAPRE1. Each is linked with POFUT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both POFUT1-to-partner and partner-to-POFUT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POFUT1 versus TM9SF4 in COAD, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POFUT1→partner) and Y-score (partner→POFUT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TM9SF4 →	+0.831	+0.497	<.001	<.001	3	6
COAD	ASXL1 →	+0.718	+0.420	<.001	<.001	3	6
COAD	MAPRE1 →	+0.591	+0.638	<.001	<.001	3	5
COAD	PIGU →	+0.565	+0.477	<.001	<.001	3	5
BRCA	FKBP9 →	+0.753	+0.378	<.001	<.001	3	5
COAD	PIGT →	+0.597	+0.471	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,850 associations by consensus.

POFUT1 vs TM9SF4 — COAD

Explore this scatter interactively →