POFUT1

Across TCGA cell cohorts, POFUT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,660 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible POFUT1-associated GO terms across cancer lineages are Mitotic centrosome separation, Nucleic acid transport, and RNA transport. Each is linked with POFUT1 in more than 15 cancer types. Because this analysis shows association rather than direction, both POFUT1-to-partner and partner-to-POFUT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic centrosome separation grouped by POFUT1-low versus POFUT1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POFUT1→partner) and Y-score (partner→POFUT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Mitotic centrosome separation →	+0.178	+1.040	<.001	<.001	3	16
STOMACH	Nucleic acid transport →	+0.109	+1.241	.004	.001	3	14
STOMACH	RNA transport →	+0.109	+1.241	.004	.001	3	14
OESOPHAGUS	Protein insertion into ER membrane →	+0.112	+1.105	.002	.002	1	16
STOMACH	Positive regulation of viral process →	+0.072	+0.820	<.001	<.001	3	14
BONE	Multi-pass transmembrane protein insertion into ER membrane →	+0.121	+0.842	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,660 associations by consensus.

Mitotic centrosome separation by POFUT1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →