POF1B

Across TCGA patient cohorts, POF1B protein abundance is significantly associated with the RNA expression of many other genes, with 13,233 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POF1B-associated genes across cancer lineages are SLC9A2, CYP3A5, and LAD1. Each is linked with POF1B in more than 5 cancer types. Because this analysis shows association rather than direction, both POF1B-to-partner and partner-to-POF1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POF1B versus SLC9A2 in LSCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POF1B→partner) and Y-score (partner→POF1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SLC9A2 →	+1.433	+1.088	<.001	<.001	3	6
LUAD	CYP3A5 →	+1.506	+1.002	<.001	<.001	3	5
CCRCC	LAD1 →	+1.230	+1.049	.001	.002	3	5
COAD	MANSC1 →	+0.701	+0.485	<.001	<.001	2	6
BRCA	PRR15 →	+1.682	+0.771	<.001	<.001	3	5
LSCC	CEACAM5 →	+2.280	+1.020	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,233 associations by consensus.

POF1B vs SLC9A2 — LSCC

Explore this scatter interactively →