POF1B

Across TCGA cell cohorts, POF1B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,417 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible POF1B-associated GO terms across cancer lineages are Peptidyl-lysine oxidation, Response to copper ion, and Positive regulation of endothelial cell development. Each is linked with POF1B in more than 10 cancer types. Because this analysis shows association rather than direction, both POF1B-to-partner and partner-to-POF1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine oxidation grouped by POF1B-low versus POF1B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POF1B→partner) and Y-score (partner→POF1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Peptidyl-lysine oxidation →	-1.328	-2.052	<.001	<.001	3	11
LARGE_INTESTINE	Response to copper ion →	-0.147	-2.259	<.001	.001	3	10
LUNG_NSCLC_LUSC	Positive regulation of endothelial cell development →	+0.248	+2.627	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Positive regulation of establishment of endothelial barrier →	+0.248	+2.627	<.001	<.001	3	9
BREAST	Cardiac muscle thin filament assembly →	+0.966	+1.520	<.001	.001	3	9
STOMACH	Negative regulation of NK T cell activation →	+0.234	+2.564	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,417 associations by consensus.

Peptidyl-lysine oxidation by POF1B expression — URINARY_TRACT

Explore this box plot interactively →