PODXL2

Across TCGA patient cohorts, PODXL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,419 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PODXL2-associated proteins across cancer lineages are PLIN3, SMARCA4, and SMARCE1. Each is linked with PODXL2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PODXL2-to-partner and partner-to-PODXL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PODXL2 versus PLIN3 in GBM, with a Pearson correlation of -0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PODXL2→partner) and Y-score (partner→PODXL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLIN3 →	-0.310	-0.717	<.001	<.001	3	5
GBM	SMARCA4 →	+0.314	+0.867	<.001	<.001	3	5
GBM	SMARCE1 →	+0.295	+0.893	<.001	<.001	3	5
BRCA	MED23 →	+0.179	+0.907	.004	.006	3	5
GBM	GATAD2B →	+0.291	+0.788	<.001	<.001	3	5
LSCC	GTF3C4 →	+0.360	+1.440	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,419 associations by consensus.

PODXL2 vs PLIN3 — GBM

Explore this scatter interactively →