PODXL2

Across TCGA cell cohorts, PODXL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,091 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PODXL2-associated GO terms across cancer lineages are Alcohol biosynthetic process, Transcription pausing by RNA polymerase II, and Cerebral cortex GABAergic interneuron migration. Each is linked with PODXL2 in more than 10 cancer types. Because this analysis shows association rather than direction, both PODXL2-to-partner and partner-to-PODXL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Alcohol biosynthetic process grouped by PODXL2-low versus PODXL2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PODXL2→partner) and Y-score (partner→PODXL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Alcohol biosynthetic process →	+0.091	+2.045	<.001	.001	3	11
LUNG_SCLC	Transcription pausing by RNA polymerase II →	+0.086	+1.417	.004	<.001	3	9
LUNG_SCLC	Cerebral cortex GABAergic interneuron migration →	+0.786	+1.027	.001	.001	3	9
LUNG_SCLC	Cerebral cortex GABAergic interneuron development →	+0.786	+1.027	.001	.001	3	9
BONE	Regulation of calcium ion transport into cytosol →	-0.322	-2.761	<.001	<.001	3	9
SKIN	Positive regulation of potassium ion transport →	-0.139	-1.531	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,091 associations by consensus.

Alcohol biosynthetic process by PODXL2 expression — SKIN

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