POC5

Across TCGA cell cohorts, POC5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,832 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible POC5-associated GO terms across cancer lineages are Centriole elongation, Regulation of centriole elongation, and Nuclear envelope organization. Each is linked with POC5 in more than 16 cancer types. Because this analysis shows association rather than direction, both POC5-to-partner and partner-to-POC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centriole elongation grouped by POC5-low versus POC5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POC5→partner) and Y-score (partner→POC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Centriole elongation →	+0.141	+0.793	.001	.005	3	17
BLOOD_Myeloma	Regulation of centriole elongation →	+0.130	+1.358	<.001	<.001	3	16
OVARY	Nuclear envelope organization →	+0.068	+0.406	<.001	.005	3	15
LUNG_NSCLC_LUSC	Positive regulation of maintenance of sister chromatid cohesion →	+0.127	+0.905	.001	.002	3	14
LUNG_NSCLC_LUSC	Positive regulation of maintenance of mitotic sister chromatid cohesion →	+0.127	+0.905	.001	.002	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.141	+0.896	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,832 associations by consensus.

Centriole elongation by POC5 expression — BONE

Explore this box plot interactively →