POC1B-GALNT4

Across TCGA pan-cancer cohorts, POC1B-GALNT4 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated POC1B-GALNT4 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher POC1B-GALNT4 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated POC1B-GALNT4 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

ACC, OV, and UCEC are the cancer types where POC1B-GALNT4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.145	0.888	<.001	45	view →
OV	DFS	Median	II,III,IV	0.214	0.541	.023	18	view →
UCEC	DFS	Median	III,IV	1.000	0.535	.023	14	view →
BLCA	OS	Median	IV	0.089	0.599	<.001	12	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

POC1B-GALNT4–ACC (OS)

Open the ACC breakdown →