POC1A

Across TCGA patient cohorts, POC1A protein abundance is significantly associated with the RNA expression of many other genes, with 1,057 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POC1A-associated genes across cancer lineages are PSENEN, TMPRSS11D, and PF4. Each is linked with POC1A in more than 1 cancer types. Because this analysis shows association rather than direction, both POC1A-to-partner and partner-to-POC1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POC1A versus PSENEN in UCEC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POC1A→partner) and Y-score (partner→POC1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PSENEN →	+0.926	+0.473	<.001	<.001	3	2
LUAD	TMPRSS11D →	-1.171	-0.337	.008	.009	3	2
GBM	PF4 →	+1.121	+0.664	.001	.005	3	2
LUAD	HS3ST5 →	-1.191	-0.379	<.001	<.001	3	2
UCEC	RSPH14 →	+1.155	+0.411	<.001	<.001	3	1
UCEC	RAB36 →	+0.867	+0.386	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,057 associations by consensus.

POC1A vs PSENEN — UCEC

Explore this scatter interactively →