Across TCGA patient cohorts, PNRC2 mutation is significantly associated with the RNA expression of many other genes, with 2,309 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PNRC2-associated genes across cancer lineages are RNA5SP222, RN7SL318P, and RN7SKP60. Each is linked with PNRC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PNRC2-to-partner and partner-to-PNRC2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PNRC2→partner) and Y-score (partner→PNRC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP222 →	+0.286	+7.731	<.001	.009	3	2
UCEC	RN7SL318P →	+0.190	+2.008	.001	.002	3	2
UCEC	RN7SKP60 →	+0.150	+2.170	<.001	.007	3	2
BRCA	RNU6-445P →	+0.247	+7.731	<.001	.009	3	1
UCEC	PGAP2 →	+0.358	+2.673	.007	<.001	3	1
UCEC	SSRP1 →	+0.455	+2.513	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,309 associations by consensus.

Exploration

PNRC2 survival (RNA) · tumor vs normal (RNA) · all PNRC2 data types