Across TCGA cell cohorts, PNRC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,028 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PNRC2-associated GO terms across cancer lineages are DNA replication checkpoint signaling, Regulation of DNA stability, and Sister chromatid segregation. Each is linked with PNRC2 in more than 11 cancer types. Because this analysis shows association rather than direction, both PNRC2-to-partner and partner-to-PNRC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PNRC2→partner) and Y-score (partner→PNRC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	DNA replication checkpoint signaling →	+0.159	+0.702	.004	.006	3	12
BLOOD_Leukemia	Regulation of DNA stability →	+0.118	+0.636	<.001	<.001	3	12
BLOOD_Myeloma	Sister chromatid segregation →	+0.096	+0.745	.002	<.001	3	11
BONE	Mitotic DNA replication checkpoint signaling →	+0.138	+0.693	.007	<.001	2	12
BONE	Regulation of DNA repair →	+0.075	+0.864	.002	<.001	3	11
BLOOD_Myeloma	Microtubule cytoskeleton organization involved in mitosis →	+0.091	+0.883	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,028 associations by consensus.

Exploration

PNRC2 survival (RNA) · tumor vs normal (RNA) · all PNRC2 data types