Q-omics provides the consensus-scored PNPLA4P1 profile across patient tissues and cancer cell-line models. PNPLA4P1 expression is associated with patient survival in 6 of 34 cancer types, with the highest sampling consensus in UCEC. Additionally, PNPLA4P1 RNA expression shows 3,904 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight UCEC, and ESCA as cancer lineages where PNPLA4P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Premium analyses for PNPLA4P1 — synthetic lethality, tumor antigen, and pembrolizumab response.

View premium →

Survival associations

This table summarizes PNPLA4P1 survival associations across molecular data types. PNPLA4P1 RNA expression shows survival associations in the most cancer types (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

PNPLA4P1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	6	DLBC (90)	view →

This table ranks reproducible PNPLA4P1 RNA expression–survival associations across cancer types. High PNPLA4P1 expression shows unfavorable associations in UCEC, DLBC, HNSC, BRCA, LAML and SARC. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCEC as the clearest survival context for PNPLA4P1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	II,III,IV	0.206	0.825	<.001	90	view →
DLBC	OS	Tertile	II,III,IV	0.099	0.731	.005	90	view →
HNSC	DFS	Tertile	All	0.094	0.710	<.001	54	view →
BRCA	OS	Tertile	III,IV	0.233	0.833	<.001	36	view →
LAML	DFS	Tertile	All	0.027	0.583	<.001	18	view →
SARC	DFS	Tertile	All	0.118	0.591	.034	9	view →

Pink = unfavorable, green = favorable. all 6 lineages →

PNPLA4P1-UCEC (DFS)

Kaplan–Meier survival curve for PNPLA4P1 RNA expression in UCEC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with PNPLA4P1 in patient tissues and cancer cell lines. In patient samples, PNPLA4P1 shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	3,904	ESCA (2262)	view →
Function (RNA)	3,304	STAD (3287)	view →