PNPLA10P

Across TCGA pan-cancer cohorts, PNPLA10P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated PNPLA10P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher PNPLA10P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PNPLA10P expression acts as an unfavorable survival marker, although some lineages such as THCA show a favorable association.

BLCA, KIRC, and SKCM are the cancer types where PNPLA10P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	III,IV	0.082	0.582	<.001	36	view →
KIRC	DFS	Tertile	All	0.517	0.650	.004	33	view →
SKCM	OS	Tertile	II,III,IV	0.608	0.855	<.001	30	view →
PAAD	DFS	Tertile	II,III,IV	0.183	0.441	.019	18	view →
LIHC	OS	Tertile	II,III,IV	0.171	0.701	<.001	18	view →
LUAD	OS	Tertile	III,IV	0.173	0.663	.018	18	view →
PCPG	DFS	Tertile	All	0.195	0.833	.002	9	view →
READ	DFS	Tertile	IV	0.255	0.628	.020	9	view →
THCA	DFS	Tertile	All	1.000	0.817	.039	6	view →
STAD	DFS	Quartile	IV	0.087	0.524	.005	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

PNPLA10P–BLCA (OS)

Open the BLCA breakdown →