Across TCGA cell cohorts, PNP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,314 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible PNP-associated GO terms across cancer lineages are Purine deoxyribonucleoside catabolic process, Deoxyguanosine catabolic process, and Maturation of SSU-rRNA. Each is linked with PNP in more than 11 cancer types. Because this analysis shows association rather than direction, both PNP-to-partner and partner-to-PNP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PNP→partner) and Y-score (partner→PNP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Purine deoxyribonucleoside catabolic process →	+0.571	+1.440	<.001	<.001	3	12
SKIN	Deoxyguanosine catabolic process →	+0.571	+1.440	<.001	<.001	3	12
CNS	Maturation of SSU-rRNA →	+0.103	+1.157	<.001	<.001	3	11
BREAST	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.081	+0.846	<.001	.004	3	11
KIDNEY	Purine ribonucleoside salvage →	+0.193	+0.996	<.001	.001	3	11
BLOOD_Lymphoma	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.102	+1.215	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,314 associations by consensus.

Exploration

PNP survival (RNA) · tumor vs normal (RNA) · all PNP data types