PNMA8C

Across TCGA cell cohorts, PNMA8C RNA expression is significantly associated with the go_rna of many other GO terms, with 968 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible PNMA8C-associated GO terms across cancer lineages are Establishment of protein localization to organelle, Translational initiation, and Mitotic cytokinesis. Each is linked with PNMA8C in more than 8 cancer types. Because this analysis shows association rather than direction, both PNMA8C-to-partner and partner-to-PNMA8C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to organelle grouped by PNMA8C-low versus PNMA8C-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PNMA8C→partner) and Y-score (partner→PNMA8C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Establishment of protein localization to organelle →	+0.035	+0.367	.002	.008	3	9
CNS	Translational initiation →	+0.035	+0.271	.003	.001	3	6
LUNG_SCLC	Mitotic cytokinesis →	+0.074	+0.857	<.001	.003	3	5
CNS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.094	+0.496	<.001	<.001	3	5
CNS	Protein localization to nucleus →	+0.035	+0.425	.002	.005	3	5
CNS	Negative regulation of myoblast fusion →	+0.094	+0.462	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 968 associations by consensus.

Establishment of protein localization to organelle by PNMA8C expression — CNS

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