Across TCGA cell cohorts, PNMA5 RNA expression is significantly associated with the go_rna of many other GO terms, with 944 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PNMA5-associated GO terms across cancer lineages are Protein destabilization, Maintenance of protein localization in endoplasmic reticulum, and ERAD pathway. Each is linked with PNMA5 in more than 4 cancer types. Because this analysis shows association rather than direction, both PNMA5-to-partner and partner-to-PNMA5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PNMA5→partner) and Y-score (partner→PNMA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Protein destabilization →	+0.076	+0.068	<.001	.002	3	5
KIDNEY	Maintenance of protein localization in endoplasmic reticulum →	+0.155	+0.105	.001	.009	3	5
LARGE_INTESTINE	ERAD pathway →	+0.057	+0.103	<.001	.001	3	5
LARGE_INTESTINE	Negative regulation of mRNA metabolic process →	+0.058	+0.076	.001	<.001	3	4
PANCREAS	Positive regulation of transcription by RNA polymerase III →	+0.101	+0.053	.001	.008	3	4
LARGE_INTESTINE	Regulation of protein K48-linked ubiquitination →	+0.072	+0.066	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 944 associations by consensus.

Exploration

PNMA5 survival (RNA) · tumor vs normal (RNA) · all PNMA5 data types