PNMA2

Across TCGA patient cohorts, PNMA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,645 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PNMA2-associated proteins across cancer lineages are DPYSL2, VIM, and SEPTIN11. Each is linked with PNMA2 in more than 7 cancer types. Because this analysis shows association rather than direction, both PNMA2-to-partner and partner-to-PNMA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PNMA2 versus DPYSL2 in OV, with a Pearson correlation of 0.81.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PNMA2→partner) and Y-score (partner→PNMA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DPYSL2 →	+1.102	+1.626	<.001	<.001	3	8
LSCC	VIM →	+0.482	+0.783	<.001	<.001	3	6
BRCA	SEPTIN11 →	+0.473	+1.037	<.001	<.001	3	6
OV	LUM →	+0.742	+1.180	.001	.001	3	6
BRCA	VIM_S22 →	+0.653	+0.605	<.001	<.001	3	5
PDAC	YME1L1 →	-0.345	-0.819	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,645 associations by consensus.

PNMA2 vs DPYSL2 — OV

Explore this scatter interactively →