PNMA2

Across TCGA patient cohorts, PNMA2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,845 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PNMA2-associated genes across cancer lineages are PSME2P5, MGAT1, and MIPOL1. Each is linked with PNMA2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PNMA2-to-partner and partner-to-PNMA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PNMA2 versus PSME2P5 in CCRCC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PNMA2→partner) and Y-score (partner→PNMA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PSME2P5 →	+1.010	+0.785	<.001	<.001	3	5
LUAD	MGAT1 →	+0.310	+0.752	<.001	<.001	3	3
GBM	MIPOL1 →	-0.680	-0.820	.001	<.001	3	3
LUAD	CD300C →	+0.666	+0.621	<.001	<.001	3	3
LUAD	DPYSL2 →	+0.663	+0.728	<.001	<.001	3	3
CCRCC	PIGH →	-0.341	-0.466	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,845 associations by consensus.

PNMA2 vs PSME2P5 — CCRCC

Explore this scatter interactively →