PNMA2

Across TCGA cell cohorts, PNMA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,530 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PNMA2-associated GO terms across cancer lineages are Transport of virus, Intracellular transport of virus, and Cytoplasmic translation. Each is linked with PNMA2 in more than 8 cancer types. Because this analysis shows association rather than direction, both PNMA2-to-partner and partner-to-PNMA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transport of virus grouped by PNMA2-low versus PNMA2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PNMA2→partner) and Y-score (partner→PNMA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Transport of virus →	+0.202	+2.697	.002	.001	3	9
LUNG_NSCLC_LUSC	Intracellular transport of virus →	+0.202	+2.697	.002	.001	3	9
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.071	+0.772	.005	.009	3	9
BREAST	Protein localization to nucleus →	+0.059	+1.105	<.001	.003	3	8
BLOOD_Leukemia	Sensory perception of mechanical stimulus →	-0.041	-1.074	<.001	.006	3	8
OVARY	Negative regulation of bone mineralization involved in bone maturation →	+1.084	+1.579	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,530 associations by consensus.

Transport of virus by PNMA2 expression — LUNG_NSCLC_LUSC

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