PNMA1

Across TCGA patient cohorts, PNMA1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,331 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PNMA1-associated genes across cancer lineages are MOK, NOVA1, and CAND2. Each is linked with PNMA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PNMA1-to-partner and partner-to-PNMA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PNMA1 versus MOK in HNSC, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PNMA1→partner) and Y-score (partner→PNMA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MOK →	+0.978	+0.718	.008	.002	2	6
BRCA	NOVA1 →	+1.285	+0.327	.003	.007	3	4
LSCC	CAND2 →	+0.795	+0.637	.001	<.001	3	4
GBM	BSN →	+0.874	+0.261	<.001	<.001	3	4
GBM	TECPR2 →	+0.496	+0.439	<.001	<.001	3	4
BRCA	SDR39U1 →	+0.389	+0.311	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,331 associations by consensus.

PNMA1 vs MOK — HNSC

Explore this scatter interactively →