PNMA1

Across TCGA cell cohorts, PNMA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,589 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PNMA1-associated GO terms across cancer lineages are Positive regulation of ubiquitin-dependent protein catabolic process, Host-mediated perturbation of viral process, and Transport along microtubule. Each is linked with PNMA1 in more than 11 cancer types. Because this analysis shows association rather than direction, both PNMA1-to-partner and partner-to-PNMA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of ubiquitin-dependent protein catabolic process grouped by PNMA1-low versus PNMA1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PNMA1→partner) and Y-score (partner→PNMA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.057	+1.086	<.001	<.001	3	12
KIDNEY	Host-mediated perturbation of viral process →	+0.061	+0.803	.009	.005	3	12
LUNG_SCLC	Transport along microtubule →	+0.044	+0.625	.002	.001	3	11
CNS	Positive regulation of cell-substrate junction organization →	+0.088	+0.725	<.001	<.001	3	11
LARGE_INTESTINE	Cellular response to aldosterone →	-0.332	-1.467	<.001	<.001	3	11
STOMACH	Response to aldosterone →	-0.186	-1.139	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,589 associations by consensus.

Positive regulation of ubiquitin-dependent protein catabolic process by PNMA1 expression — KIDNEY

Explore this box plot interactively →