PNLIPRP3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PNLIPRP3 mutation is significantly associated with the RNA expression of many other genes, with 3,054 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PNLIPRP3-associated genes across cancer lineages are RNU6-61P, RNU6-1207P, and RNA5SP113. Each is linked with PNLIPRP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both PNLIPRP3-to-partner and partner-to-PNLIPRP3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PNLIPRP3→partner) and Y-score (partner→PNLIPRP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNU6-61P →+0.349+4.969<.001.00433
LUADRNU6-1207P →+0.388+3.213<.001.00633
UCECRNA5SP113 →+0.273+2.418<.001.00633
UCECYBX1P2 →+0.453+2.534<.001<.00133
UCECGNPDA1 →+0.512+2.115<.001<.00133
UCECPPIL1 →+0.476+2.687.002<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,054 associations by consensus.

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