PNLIPRP3

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PNLIPRP3 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PNLIPRP3-associated genes across cancer lineages are Caspase-7-cleavedD198, Bax, and INPP4B. Each is linked with PNLIPRP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both PNLIPRP3-to-partner and partner-to-PNLIPRP3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PNLIPRP3→partner) and Y-score (partner→PNLIPRP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCCaspase-7-cleavedD198 →+0.695+2.594<.001.00633
LUSCBax →+0.210+1.883.025.03132
UCECINPP4B →-0.241-1.700.028.04032
UCECJNK_pT183_Y185 →-0.141-3.000.013<.00132
UCECPCNA →+0.278+2.523<.001<.00132
UCECRAD51 →+0.096+1.700.043.04232
Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Exploration