Across TCGA pan-cancer cohorts, PNLIPRP1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of PNLIPRP1’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where PNLIPRP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PNLIPRP1 is over-expressed in tumor, although a few such as THCA and COAD show the opposite, repressed pattern.
BRCA, THCA, and LUAD are the cancer types where PNLIPRP1 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PNLIPRP1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.