PNLIP

Across TCGA cell cohorts, PNLIP RNA expression is significantly associated with the mutation status of many other genes, with 75 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible PNLIP-associated genes across cancer lineages are APOB, COL4A6, and TPR. Each is linked with PNLIP in more than 1 cancer types. Because this analysis shows association rather than direction, both PNLIP-to-partner and partner-to-PNLIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, APOB grouped by PNLIP-low versus PNLIP-high in CNS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PNLIP→partner) and Y-score (partner→PNLIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	APOB →	+1.979	+0.074	.009	<.001	3	2
OVARY	COL4A6 →	+3.990	+0.039	.003	<.001	3	2
LUNG_SCLC	TPR →	+2.684	+0.084	.007	.001	3	2
PANCREAS	ABCC11 →	+4.786	+0.012	.001	<.001	3	1
PANCREAS	CEP350 →	+3.201	+0.007	.008	<.001	3	1
PANCREAS	LCN2 →	+4.786	+0.006	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 75 associations by consensus.

APOB by PNLIP expression — CNS

Explore this box plot interactively →