PNLDC1

Across TCGA patient cohorts, PNLDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,044 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible PNLDC1-associated GO terms across cancer lineages are Regulation of post-translational protein modification, Regulation of membrane permeability, and Chaperone-mediated protein folding. Each is linked with PNLDC1 in more than 15 cancer types. Because this analysis shows association rather than direction, both PNLDC1-to-partner and partner-to-PNLDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of post-translational protein modification grouped by PNLDC1-low versus PNLDC1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PNLDC1→partner) and Y-score (partner→PNLDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of post-translational protein modification →	+0.054	+0.241	<.001	<.001	3	16
STAD	Regulation of membrane permeability →	+0.050	+0.256	<.001	<.001	3	16
STAD	Chaperone-mediated protein folding →	+0.101	+0.390	<.001	<.001	3	16
STAD	Regulation of stem cell population maintenance →	+0.092	+0.312	<.001	<.001	3	15
STAD	Positive regulation of telomerase RNA localization to Cajal body →	+0.050	+0.255	<.001	<.001	3	15
STAD	rRNA transcription →	+0.098	+0.370	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,044 associations by consensus.

Regulation of post-translational protein modification by PNLDC1 expression — STAD

Explore this box plot interactively →