PNLDC1

Across TCGA cell cohorts, PNLDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,012 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PNLDC1-associated GO terms across cancer lineages are DNA-templated DNA replication maintenance of fidelity, U2-type prespliceosome assembly, and Double-strand break repair. Each is linked with PNLDC1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PNLDC1-to-partner and partner-to-PNLDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication maintenance of fidelity grouped by PNLDC1-low versus PNLDC1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PNLDC1→partner) and Y-score (partner→PNLDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated DNA replication maintenance of fidelity →	+0.099	+0.069	.002	<.001	2	7
BONE	U2-type prespliceosome assembly →	+0.110	+0.067	.005	.006	2	7
LARGE_INTESTINE	Double-strand break repair →	+0.035	+0.055	<.001	<.001	3	6
BONE	Constitutive heterochromatin formation →	+0.070	+0.068	.003	<.001	3	5
BONE	Replication fork processing →	+0.098	+0.063	.003	.001	2	6
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.114	+0.062	.002	.008	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,012 associations by consensus.

DNA-templated DNA replication maintenance of fidelity by PNLDC1 expression — BONE

Explore this box plot interactively →