PNKD

Across TCGA cell cohorts, PNKD RNA expression is significantly associated with the RNA expression of many other genes, with 7,724 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PNKD-associated genes across cancer lineages are UQCR10, AAMP, and NDUFB3. Each is linked with PNKD in more than 11 cancer types. Because this analysis shows association rather than direction, both PNKD-to-partner and partner-to-PNKD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PNKD versus UQCR10 in URINARY_TRACT, with a Pearson correlation of 0.70.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PNKD→partner) and Y-score (partner→PNKD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	UQCR10 →	+1.041	+1.101	<.001	<.001	3	12
BREAST	AAMP →	+0.823	+0.861	<.001	<.001	2	12
STOMACH	NDUFB3 →	+1.057	+0.895	.001	<.001	2	12
UPPER_AERODIGESTIVE_TRACT	ATP5PF →	+1.087	+0.892	<.001	.001	2	11
BREAST	CHCHD1 →	+0.722	+0.585	.004	.003	3	9
OESOPHAGUS	DPM3 →	+1.688	+1.345	<.001	<.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,724 associations by consensus.

PNKD vs UQCR10 — URINARY_TRACT

Explore this scatter interactively →